Suppression of mitogen-induced lymphocyte proliferation by syringomycin-E

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Suppression of mitogen-induced lymphocyte proliferation by syringomycin-E.

Syringomycin E (SR-E) is a low molecular weight bacterial lipodepsipeptide with antifungal properties. Owing to immunosuppressive activities of such compounds as cyclosporine, FK506 and rapamycin, we studied the effect of SR-E on proliferation of human blood lymphocytes in vitro. SR-E, by itself, had no effect but the mitogen-induced lymphocyte proliferation was significantly suppressed. The su...

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ژورنال

عنوان ژورنال: FEMS Immunology & Medical Microbiology

سال: 1996

ISSN: 0928-8244,1574-695X

DOI: 10.1111/j.1574-695x.1996.tb00069.x